Week 16 NFL Picks

All betting lines from bet365.com (Updated Dec. 21)

Los Angeles Rams (11-3) @ Seattle Seahawks (11-3)

Pivotal NFC West matchup here as the Rams come into this red hot and the connection between Matthew Stafford and Puka Nacua operating at an elite level. Interestingly enough, this division is still up for grabs if the Niners can win on Monday night. Pick: Rams, 27-24.

Line: Seahawks -1.5

ML: Rams

Spread: Rams

Philadelphia Eagles (9-5) @ Washington Commanders (4-10)

With a win this week, the Eagles can end a 21-year streak of no repeat division winner in the NFC East. The defense has played well, but it has been their offense that has shown inconsistency over the course of the season. This is a get right spot for the birds. Pick: Eagles, 27-14.

Line: Eagles -7

ML: Eagles

Spread: Eagles

Green Bay Packers (9-4-1) @ Chicago Bears (10-4)

This is basically a game for the NFC North title as the winner has a better than 80% chance to win the division with a win here. The loss of Micah Parsons will hurt the pass rush, but I think the Packers will have enough to grind this game out in weather conditions that could play a factor in the kicking game. Pick: Packers, 20-17.

Line: Bears -1

ML: Packers

Spread: Packers

Tampa Bay Buccaneers (7-7) @ Carolina Panthers (7-7)

The winner of this game will put themselves in great position to win the NFC South crown and host a playoff game in January. The Bucs let a two score lead slip through their hands last week and will need a short memory to get set for this matchup. The Panthers look like a different team at home this year, going 4-2, and I think they could surprise the Bucs this week. Pick: Panthers, 26-24.

Line: Buccaneers -3

ML: Panthers

Spread: Panthers

Buffalo Bills (10-4) @ Cleveland Browns (3-11)

The Bills came away with a huge win on the road over the Pats last week and are in prime position to steal the AFC East away from them. The Browns are very much going through growing pains and will get the chance to see what Shedeur Sanders is made of the rest of the way. Pick: Bills, 27-16.

Line: Bills -10.5

ML: Bills

Spread: Bills

Los Angeles Chargers (10-4) @ Dallas Cowboys (6-7-1)

The Chargers come in fresh off knocking the Chiefs out of the playoff picture and with a win, they will cement their spot in the playoffs. The Cowboys on the other hand are simply playing for pride and George Pickens in particular is likely playing for a new contract. Pick: Chargers, 27-24.

Line: Cowboys -1.5

ML: Chargers

Spread: Chargers

New York Jets (3-11) @ New Orleans Saints (4-10)

The Saints have been playing well offensively the last couple of weeks and Tyler Shough is showing some potential under center. Both of these teams are on track for a high pick in next year's draft. Pick: Saints, 24-17.

Line: Saints -6.5

ML: Saints

Spread: Saints

Minnesota Vikings (6-8) @ New York Giants (2-12)

J.J. McCarthy had his best game of the year last week, torching the Cowboys' secondary and will now face a tough pass rush from the Giants. These last few weeks are all about building an offensive foundation for next season and growing chemistry with Justin Jefferson. Pick: Vikings, 24-16.

Line: Vikings -2.5

ML: Vikings

Spread: Vikings

Kansas City Chiefs (6-8) @ Tennessee Titans (2-12)

The Chiefs have been eliminated from the playoffs for the first time in the Andy Reid and Patrick Mahomes era. The biggest question mark heading into the offseason will be surrounding Travis Kelce's future with the team. Pick: Chiefs, 23-17.

Line: Chiefs -2.5

ML: Chiefs

Spread: Chiefs

Cincinnati Bengals (4-10) @ Miami Dolphins (6-8)

The Dolphins made the brash decision to bench Tua Tagovailoa this week in favor of Quinn Ewers. Will this be the end of his time in Miami? Pick: Bengals, 30-23.

Line: Bengals -4

ML: Bengals

Spread: Bengals

Atlanta Falcons (5-9) @ Arizona Cardinals (3-11)

Both of these teams are playing for pride this week and I'll give the edge to the Falcons, who are coming off a comeback win last Thursday over the Bucs. Pick: Falcons, 26-21.

Line: Falcons -3

ML: Falcons

Spread: Falcons

Jacksonville Jaguars (10-4) @ Denver Broncos (12-2)

This is one of the better matchups on the schedule this week as the Broncos look to remain undefeated at home. The Jags have a lot to play for as they try to hold off the Texans for the AFC South lead. Pick: Broncos, 31-24.

Line: Broncos -3.5

ML: Broncos

Spread: Broncos

Pittsburgh Steelers (8-6) @ Detroit Lions (8-6)

The Lions are the more desperate team heading into this matchup, needing a win to keep their playoff hopes alive. If they can win out, they still have an outside shot at the division title. Pick: Lions, 27-23.

Line: Lions -7

ML: Lions

Spread: Steelers

Las Vegas Raiders (2-12) @ Houston Texans (9-5)

In what should be an absolute wash for the Texans, they have clawed their way back into a position to steal the AFC South title from the Colts and Jags. The defense has been stellar, and C.J. Stroud seems to be finding his groove at the right time. Pick: Texans, 31-15.

Line: Texans -14

ML: Texans

Spread: Texans

New England Patriots (11-3) @ Baltimore Ravens (7-7)

The Ravens absolutely need this game as they continue to battle with the Steelers for the division lead. It's a tall task for Jon Harbaugh's crew as the Pats have been one of the most consistent teams on both sides of the ball from start to finish this season. Pick: Ravens, 27-23.

Line: Ravens -3

ML: Ravens

Spread: Ravens

San Francisco 49ers (10-4) @ Indianapolis Colts (8-6)

Just a month ago it looked like the Colts were going to run away with the AFC South title, but an injury to Daniel Jones has changed the course of this season. The Niners are getting healthy at the right time and could end up the NFC West champs by the end of the year. Pick: 49ers, 28-20.

Line: 49ers -5.5

ML: 49ers

Spread: 49ers

Results

Week 15

ML: 10-6

ATS: 10-6

Overall

ML: 146-78 (65.2%)

ATS: 117-105-2 (52.2%)