The Bills and Jags headline this week's wild card matchups. Can the Bills snap a 32-year road playoff drought?

The Niners host the Seahawks in a battle for the NFC West title. Can Sam Darnold join Tom Brady as the only two quarterbacks in NFL history with back-to-back 14-win seasons?

The Rams and Seahawks headline Week 16 in a huge NFC West clash. Will Stafford and Nacua's magic be enough to cement the win?

The Broncos and Packers square off in a game that could lock up the AFC West title for the Sean Payton and Bo Nix.

Week 13 is loaded with key matchups, especially on Thanksgiving Day. Can Joe Burrow stun the Ravens in his return to the field?

The Cowboys and Eagles meet for the second time this season. Will Week 12 bring a different result than opening night?

Week 11 offers several pivotal matchups with playoff implications, perhaps none bigger than an NFC West clash between the Rams and Seahawks.

**All betting lines from bet365.com** (Updated Nov. 9) Las Vegas Raiders (2-6) @ Denver Broncos (7-2) The Broncos narrowly escaped with a win on the road in Houston last week and find themselves atop the AFC West. I think Bo Nix has been inconsistent, but their defense is elite and should carry them to a win here. Pick: Broncos, 24-13. Line: Broncos -9 ML: Broncos Spread: Broncos Atlanta Falcons (3-5) @ Indianapolis Colts (7-2) This game will be played in Germany, which

A pivotal matchup in Week 8 features the Cowboys and Broncos, two teams looking to cement their way in the playoffs. Will Sean Payton get the better of his former team?