The Niners host the Seahawks in a battle for the NFC West title. Can Sam Darnold join Tom Brady as the only two quarterbacks in NFL history with back-to-back 14-win seasons?

The Rams and Seahawks headline Week 16 in a huge NFC West clash. Will Stafford and Nacua's magic be enough to cement the win?

The Broncos and Packers square off in a game that could lock up the AFC West title for the Sean Payton and Bo Nix.

Week 13 is loaded with key matchups, especially on Thanksgiving Day. Can Joe Burrow stun the Ravens in his return to the field?

The Cowboys and Eagles meet for the second time this season. Will Week 12 bring a different result than opening night?

Week 11 offers several pivotal matchups with playoff implications, perhaps none bigger than an NFC West clash between the Rams and Seahawks.

**All betting lines from bet365.com**  (Updated Nov. 9) Las Vegas Raiders (2-6) @ Denver Broncos (7-2) The Broncos narrowly escaped with a win on the road in Houston last week and find themselves atop the AFC West. I think Bo Nix has been inconsistent, but their defense is elite and should carry them to a win here. Pick: Broncos, 24-13. Line:  Broncos -9 ML:  Broncos Spread:  Broncos Atlanta Falcons (3-5) @ Indianapolis Colts (7-2) This game will be played in Germany, which

A pivotal matchup in Week 8 features the Cowboys and Broncos, two teams looking to cement their way in the playoffs. Will Sean Payton get the better of his former team?

There are no undefeated teams heading into Week 7, proving that parody is at its highest in the NFL. How will some of these matchups shape the AFC and NFC playoff picture?

The Bears and Commanders battle on Monday night in a rematch of last year's Hail Mary thriller.

The Rams and Niners clash in an NFC West battle to open Week 5. Will Mac Jones be able to pull off the upset for the banged up Niners?

It's been a great first few weeks in the NFL and heading into Week 4 there are some key matchups to keep an eye on. The Bills, Chargers,...

The NFL season is in full swing with Week 3 on deck. Some surprising starts are leading the headlines, with the Kansas City Chiefs and...

Several teams are looking to avoid an 0-2 start and the Chiefs and Lions top that list. How will the Bears and Ben Johnson's return to Detroit go?

Week 1 has arrived with several key games to open the season. The Cowboys and Eagles meet Thursday night, will the defending Super Bowl champs start their season 1-0?

The Chiefs are chasing history, but can the Eagles write a different story in the Super Bowl history books?

It's championship weekend, and the Bills will look to derail the Chiefs' chances at a three-peat.

The Lions and Chiefs appear on a collision course for the Super Bowl. Can anyone knock them off in the divisional round this weekend?

The matchups are set for Wild Card weekend. Which team will survive and continue their chase at a Super Bowl?

The Bengals have a chance to claw back into a playoff spot, but will need some help in Week 18.